How do breast cancer begin?

Breast cancer usually starts in cells in the milk-producing ducts (invasive ductal carcinoma). Breast cancer can also start in glandular tissue called lobules (invasive lobular carcinoma) or in other breast cells or tissues. We know that normal breast cells can develop into cancer due to changes or mutations in genes. However, only about 1 in 10 breast cancers (10%) are related to known abnormal genes that are transmitted from parents (hereditary).

Many genes haven't been discovered yet, so women with a family history of breast cancer may have inherited an abnormal gene that doesn't show up in a genetic test. Most breast cancers (about 90%) develop from acquired (not hereditary) genetic changes that have not yet been identified. Breast cancer begins when breast cells (such as those that line the ducts and lobes) begin to grow abnormally. These cells have the potential to grow out of control and invade surrounding tissue.

When this happens, it's called invasive breast cancer. If cancer cells continue to grow, they can spread beyond the breast to other parts of the body, potentially life-threatening. Breast cancer occurs when breast cells grow out of control. Different types of breast cells become different types of breast cancer.

Most breast cancers start in the breast ducts (tubes that carry milk to the nipple) or in the lobules (glands that produce milk). These are respectively known as invasive ductal carcinoma and invasive lobular carcinoma. Other less common types of breast cancer include inflammatory breast cancer and ductal carcinoma in situ. Breast cancer is a cancer that starts in breast tissue.

It occurs when breast cells change and grow out of control. The cells usually form a tumor. Anatomical and histological origins of breast cancer. Most breast cancers originate in the lobules or ducts of the breast.

In some cases, the tumor infiltrates the skin or components of the chest wall, such as the pectoral muscles. Tumor cells are also capable of converting the microenvironment into a favorable state for the tumor to promote its growth and expansion. For more than two decades, the prevalence of genetic variations in BRCA genes in breast cancer and other types of cancer has been well researched. Within the broad group of diverse breast carcinomas, there are several types of breast cancer named according to their invasiveness in relation to the sites of the primary tumor.

Typical symptoms of IBC include swelling of the breasts, similar to inflammation, purple or red color of the skin, and the formation of bites or thickening of the skin of the breast, all of which are likely due to cancer cells blocking lymphatic vessels in the skin. Postmenopausal combination hormone therapy increases the risk of breast cancer, the chance of dying from breast cancer, and the chance that the cancer will only be detected at a more advanced stage. This segregation is consistent with literature and clinical experience, which show that ER positive and ER negative cancers define biologically distinct phenotypes that can be derived from different progenitor cells. As an injectable form of progesterone, Depo-Provera has been shown to increase the risk of breast cancer, but it does not appear to increase the risk in women five years after they stopped receiving vaccines.

Lobular carcinoma in situ is now considered benign, so it is eliminated from the breast cancer staging system. Lifestyle and personal behavior risk factors for breast cancer The vast majority (about 85%) of breast cancers occur in women with no apparent family history of breast cancer. .

Tonya Sharrai
Tonya Sharrai

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